What is the Lugano classification used for?

• A. Staging and response assessment of non-Hodgkin lymphoma (PET-CT-based)
• B. Staging and prognosis of multiple myeloma
• C. Diagnosis of leukemia
• D. Monitoring of solid tumors with CT

Answer: (A)

Staging and response assessment of non-Hodgkin lymphoma using PET-CT. The Lugano classification updates older staging systems by using metabolic imaging to stage disease and evaluate treatment response in FDG-avid lymphomas, rather than relying on size measurements alone. It relies on PET-CT results and uses the Deauville five-point scale to interpret metabolic activity, guiding categories such as complete metabolic response, partial metabolic response, stable metabolic disease, or progressive metabolic disease. This approach helps clinicians decide how well therapy is working and whether to continue, modify, or stop treatment. It’s specifically for lymphomas and isn’t used for diagnosing leukemia, isn’t the standard for staging multiple myeloma (which has its own criteria), and isn’t the usual method for monitoring solid tumors with CT alone.