Normal activated partial thromboplastin time (aPTT) range?

• A. 10-20 sec
• B. 24-34 sec
• C. 40-50 sec
• D. 60-70 sec

Answer: (B)

Activated partial thromboplastin time (aPTT) measures the time for clot formation via the intrinsic pathway after activation. In most clinical labs, the reference range is around 25–35 seconds, with many reporting about 24–34 seconds depending on the reagents and instrument used. Therefore, the range 24–34 seconds fits the normal reference range best. Values shorter than this are unusually quick, while those longer indicate prolongation due to factor deficiencies, inhibitors, or anticoagulant therapy. Since lab ranges vary slightly, it’s always good to compare to the specific reference provided by the performing lab.